Vitamin D Supplementation For The Prevention Of Acute Respiratory Tract Infection: A Randomized, Double-blinded Trial Among Young Finnish Men
Notes for this study:
||Number and percentage. Placebo: 48 (57.1) Intervention: 52 (65.0)
|Number of Subjects
In a randomized, double-blind, placebo-controlled trial, 164 young men were given 400 IU of vitamin D or placebo daily for 6 months.
After 20 weeks, 38 participants had dropped out of the study, with notably more in the placebo group. The primary outcome was the number of days absent from work, which was nonsignificantly lower for the vitamin D group on average. There was no significant difference in reporting of symptoms for cough, running nose, sore throat, fever, and common cold symptoms. When adjusted for smoking and influenza vaccination, the hazard ratio for rate of absence due to upper respiratory tract infection was 0.71 (95% CI 0.43-1.15) compared with placebo.