Effect Of Vitamin D3 Supplementation On Upper Respiratory Tract Infections In Healthy Adults: The VIDARIS Randomized Controlled Trial

Effect None
Values Number of infections (n=161 for both groups). Placebo: 611 Vitamin D: 593. Number per season (mean and SD). Placebo: 3.8 (2.2). Vitamin D: 3.7 (2.4)
Trial Design Randomized trial
Trial Length 6+ Months
Number of Subjects 322
Sex Both Genders
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 322 healthy adults were given 200,000 IU of vitamin D on the first and second months, or placebo, and 100,000IU monthly afterward for 18 months.

There were no statistically significant differences between groups for the number of upper respiratory tract episodes, infections per person, number of days of work missed, duration of symptoms, or rated severity. The mean levels of vitamin D at baseline were 29 (9) and 28 (9) ng/mL at baseline and increased to roughly 50 in the intervention group, and didn't change notably in the placebo group.

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