| Effect | None |
| Values | PSST. Mean + SD. Placebo: before 1.90±0.90, after 1.65±0.90. Vitamin D: before 1.50±0.83, after 1.29±0.72. |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 130 |
| Sex | Female |
| Age Range | 18-29 |
| Body Types | Obese, Overweight, Average |
In a randomized, double-blind, placebo-controlled trial, 130 women with premenstrual syndrome and vitamin D deficiency ( serum 25-(OH)-D <20 ng/mL) were allocated to take 2,000 IU of vitamin D or placebo every other day for 12 weeks.
At the end of 12 weeks, symptom score on the Premenstrual Symptoms Screening Tool (PSST) questionnaire was improved for most outcomes in both groups, with no statistically significantly greater improvements in either group. It should be noted that the scores weren't very severe to begin with.
