| Effect | Decrease |
| Values | 0-10 scale, 10 is most severe. Mean and SD. Placebo: before 6.10 ± 0.79, after 5.90 ± 0.85. Lactase: before 5.95 ± 1.60, after 0.20 ± 0.41. |
| Trial Design | Randomized trial |
| Trial Length | 24 hours |
| Number of Subjects | 40 |
| Sex | Both Genders |
| Age Range | 18-29, 30-44, 45-64, 65+ |
In a randomized trial with unclear blinding, 60 participants with lactase intolerance were given placebo, 9000 units of tilactase, or lactobacillus reuteri with 25 g of lactose. For our purposes, placebo vs. tilactase is the relevant comparison.Funding issues for this study:
The lactase group saw a considerable reduction in breath hydrogen, which was statistically significant compared with the placebo. They also saw substantially larger reductions in bloating, abdominal pain, flatulence, diarrhea.
Unclear funding.
