Studies related to Symptoms of Lactose Intolerance and Lactase enzyme

The Effect Of Oral Supplementation With Lactobacillus Reuteri Or Tilactase In Lactose Intolerant Patients: Randomized Trial

In a randomized trial with unclear blinding, 60 participants with lactase intolerance were given placebo, 9000 units of tilactase, or lactobacillus reuteri with 25 g of lactose. For our purposes, placebo vs. tilactase is the relevant comparison.

The lactase group saw a considerable reduction in breath hydrogen, which was statistically significant compared with the placebo. They also saw substantially larger reductions in bloating, abdominal pain, flatulence, diarrhea.

Unclear funding.