Effects Of A Paleolithic Diet On Cardiovascular Disease Risk Factors: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials

Effect Decrease
Values Average waist circumference change on a Paleo diet compared to the control diet: -0.48 mg/L (95% confidence interval: -0.79, -0.16)
Trial Design Meta analysis
Trial Length n/a
Number of Subjects 266
Sex Both Genders
Age Range 30-44, 45-64, 65+
Body Types Obese, Overweight, Average
Notes for this study:
Errors in this meta-analysis have been noted: [PMID:32348451]; the authors state that the corrections do not affect their conclusions [PMID:32348461] and that, as of July 2020, they were republishing the article [PMID:32666106].
Meta analysis of 8 studies: [PMID:30050374], [PMID:27223304], [PMID:25828624], [PMID:25349058], [PMID:24473459], [PMID:25304296], [PMID:19604407], and [PMID:17583796]. Paleo diets were not defined by the authors of the meta-analysis; control diets included Dutch, Nordic, and Australian healthy eating guidelines, conventional diabetes diets, a Mediterranean-like diet, or the participants' usual diet. Duration ranged from 2 weeks to 24 months (but outcomes at 6 months were used for the analysis if the study lasted longer). Quality of studies was mostly good, as determined with the Cochrane Collaboration Risk of Bias Tool.

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