Studies related to Insulin Resistance and Paleolithic Diet

Paleolithic Diet-Effect On The Health Status And Performance Of Athletes?

Effect None
Values HOMA-IR. Change from baseline in studies less than 6 months (weighted mean, 95% confidence intervals): Paleo Diet: -0.408 (-0.631, -0.185); Control diet: -0.074 (-0.185, 0.037). Change from baseline in studies greater than 6 months (weighted mean, 95% confidence intervals): Paleo Diet: -0.022 (-0.153, 0.109); Control diet: 0.304 (0.085, 0.523).
Trial Design Meta analysis
Trial Length n/a
Number of Subjects 700
Sex Both Genders
Age Range 18-29, 30-44, 45-64, 65+
Body Types Obese, Overweight, Average
Notes for this study:
Meta analysis of 21 studies: [PMID:27149238], [PMID:25304296], [PMID:28440046], [PMID:29075849], [PMID:26139105], [PMID:27216013], [PMID:19209185], [PMID:27223304], [PMID:17583796], [PMID:25828624], [PMID:24473459], [PMID:26786351], [PMID:17522610], [PMID:17522610], [PMID:25349058], [PMID:27235022], [PMID:29696296], [PMID:30652528], [PMID:23414424], [reference|url=https://doi.org/10.1177/1559827619866157|title=Single-Arm 8-Week Ad Libitum Self-Prepared Paleo Diet Reduces Cardiometabolic Disease Risk Factors in Overweight Adults|published=2019 Aug|authors=Markofski MM, Jennings K, Dolan C, Davies NA, LaVoy EC, Ryan EJ, Carrillo AE|journal=AJLM], and [reference|url=https://elementssystem.com/wp-content/uploads/2018/06/Smith.pdf|title=Unrestricted Paleolithic Diet is Associated with Unfavorable Changes to Blood Lipids in Healthy Subjects|published=2014 Jul|authors=Smith MM, Trexler ET, Sommer AJ, Starkoff BE, Devor ST|journal=Int J Exerc Sci], some of which are secondary analysis of a study already included. 3 studies [PMID:19209185] [PMID:23414424] [reference|url=https://doi.org/10.1177/1559827619866157|title=Single-Arm 8-Week Ad Libitum Self-Prepared Paleo Diet Reduces Cardiometabolic Disease Risk Factors in Overweight Adults|published=2019 Aug|authors=Markofski MM, Jennings K, Dolan C, Davies NA, LaVoy EC, Ryan EJ, Carrillo AE|journal=AJLM] were non-controlled trials; 3 studies [PMID:27235022] [PMID:30652528] [reference|url=https://elementssystem.com/wp-content/uploads/2018/06/Smith.pdf|title=Unrestricted Paleolithic Diet is Associated with Unfavorable Changes to Blood Lipids in Healthy Subjects|published=2014 Jul|authors=Smith MM, Trexler ET, Sommer AJ, Starkoff BE, Devor ST|journal=Int J Exerc Sci] compared a paleo diet to a paleo diet plus exercise intervention. Paleo diets encouraged grass-fed and pasture-raised meats, vegetables, fruits, fungi, roots, and nuts, limited refined sugars, starches, processed foods, and oils, and excluded grains, legumes, dairy, and refined foods; control diets were based on Dutch, Nordic, or Australian healthy eating guidelines, conventional heart-healthy and diabetes diets, a Mediterrenean diet, or a conventional low-fat diet. Duration ranged from 2 weeks to 24 months. Quality of studies was generally good.

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