| Effect | None |
| Values | Scores during menstruation. General Health Standard Questionnaire.Placebo: 12.5 ± 4.47 Intervention: 10.72 ± 3.69 |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 100 |
| Sex | Female |
| Age Range | 7-12, 13-17, 18-29 |
In a randomized, double-blind, placebo-controlled trial, 100 girls with premenstrual syndrome were allocated to take 1,200 mg of M. officinalis or placebo daily during their menstrual periods for 3 cycles. Scores on the The General Health Questionnaire, symptoms were significantly lower for the intervention group for psychosomatic symptoms, anxiety and sleep disturbances, social function disturbance, and depression.
