Studies related to Blood Glucose and Glutamine

Oral Glutamine Supplementation During Preoperative Radiochemotherapy In Patients With Rectal Cancer: A Randomised Double Blinded, Placebo Controlled Pilot Study

Effect Increase
Trial Design Double blind
Trial Length n/a
Number of Subjects 33
Gender Both Genders
Age Range 45-64, 65+
Body Types Average
Notes for this study:
Glutamine at 30g (average dose of 0.41+/-0.07g/kg bodyweight) in rectal cancer patients undergoing chemotherapy was investigated to see whether glutamine can confer gut protection during radiochemotherapy.

There were no effects of glutamine on diarrhea or inflammation that were different than placebo (maltodextrin) aside from an increase in IL-6 seen with glutamine supplementation. The increase in insulin seen was comparable, and although glucose trended to increase it did not reach significance.

A Randomized Cross-over Study Of The Metabolic And Hormonal Responses Following Two Preoperative Conditioning Drinks

Effect Decrease
Trial Design Cohort
Trial Length n/a
Number of Subjects 12
Gender n/a
Notes for this study:
In comparing 50g of maltodextrin (sugar) to the same dose of maltodextrin but paired with 15g of glutamine and anti-oxidants, it was found that serum glucose and insulin AUC were lower in the glutamine group relative to maltodextrin.