Studies related to Urea and Glutamine

The Safety Of Oral Use Of L-glutamine In Middle-aged And Elderly Individuals

Effect Increase
Trial Design Double blind
Trial Length 1-2 Weeks
Number of Subjects 30
Gender Both Genders
Age Range 65+
Body Types Average
Notes for this study:
Increases in creatinine and urea (not ammonia) were seen after oral administration of 0.5g/kg glutamine in elderly persons (69+/-8.8 years); these changes were not deemed to be clinically relevant, although they were statistically.

The glomerular filtration rate decreased 13.3%, but was considered to be below the biologically significant 25% marker. The authors thought that other biomarkers noted (increase in urea and creatinine) were due to inefficient renal excretion.