The Safety Of Oral Use Of L-glutamine In Middle-aged And Elderly Individuals
| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | 1-2 Weeks |
| Number of Subjects | 30 |
| Sex | Both Genders |
| Age Range | 65+ |
| Body Types | Average |
Increases in creatinine and urea (not ammonia) were seen after oral administration of 0.5g/kg glutamine in elderly persons (69+/-8.8 years); these changes were not deemed to be clinically relevant, although they were statistically.
The glomerular filtration rate decreased 13.3%, but was considered to be below the biologically significant 25% marker. The authors thought that other biomarkers noted (increase in urea and creatinine) were due to inefficient renal excretion.
