Efficacy And Safety Of Vitex Agnus-castus Extract For Treatment Of Premenstrual Syndrome In Japanese Patients: A Prospective, Open-label Study
Notes for this study:
|Number of Subjects
Supplementation of a vitex agnus castus supplement (Prefemin; 20mg of a 60% water-ethanolic extract; 6-12:1 concentrated) daily for three menstrual cycles in an open-label study noted that all symptoms of PMS decreased when measured at the first and third cycles compared to baseline.
Funding issues for this study:
Medication appears to be well tolerated aside from one acute reaction which appeared to be allergic dermatitis.
Some potential conflicts of interest with authors and the manufacturer of the supplement