Effect | Decrease |
Values | Compared with control. SBP: -3.03 mm Hg (95% CI: -5.04, -1.02). DBP: -0.71 mm Hg 159 (95% CI: -1.26, -0.16) |
Trial Design | Meta analysis |
Trial Length | n/a |
Number of Subjects | 0 |
Sex | n/a |
The study was a meta-analysis of randomized controlled trial that investigated the effect of soybean protein on blood pressure in postmenopausal women.
9 studies with 12 soy groups were included. Compared with control, overall, there was a reduction in systolic blood pressure of 3.03 mm Hg (95% CI: -5.04, -1.02) with notable heterogeneity and -0.71 mm Hg 159 (95% CI: -1.26, -0.16) for diastolic blood pressure without notable heterogeneity. More than 25 g per day led to a significantly greater reduction, and so did soy protein with higher isoflavone content.
There was no subgroup analysis for the type of comparator but were largely non-soy protein. 10 of 12 studies had a JADAD score of at least 3.