| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 48 |
| Sex | Female |
| Age Range | 45-64 |
| Body Types | Average |
Improvements were seen in fatigue, physical and emotional (but not social) well being, and improvements in functionality (all assessed by FACT-F survey) as well as reductions in anxiety and depression (assessed by HAD) in female breast cancer patients suffering from fatigue and undergoing endocrine therapy.
1g of ganoderma spore extract thrice daily (3g total) for four weeks was used.
TNF-a and IL-6 levels were correlated with fatigue, and were reduced after intervention.
