Studies related to Liver Damage and Ketogenic diet

Long-Term Effects Of A Novel Continuous Remote Care Intervention Including Nutritional Ketosis For The Management Of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial

Effect Decrease
Values NAFLD-Fibrosis score. Ketogenic: baseline −0.31 ± 0.06, 1 year −0.95 ± 0.07, 2 year −0.78 ± 0.08. Control: baseline −0.45 ± 0.11, 1 year −0.19 ± 0.12, 2 year −0.24 ± 0.14 .
Trial Design Non-randomized controlled trial
Trial Length 6+ Months
Number of Subjects 262
Sex Both Genders
Body Types Obese
Notes for this study:
In a non-randomized, unblinded controlled trial, 262 obese participants were educated about a ketogenic diet, planned to contain 30 g of carbohydrates. The results were published after 2 years, and a control group that received no intervention was the comparison.

After one year, 218 participants remained, and after 2, 194 remained. The ketogenic diet group was on average in mild ketosis at the end of 2 years. Participants on the ketogenic diet saw much greater weight loss in the first year but gained a smaller amount of weight back after the 2nd. The improvement in glycated hemoglobin was much greater in the ketogenic group in the first year and similarly worsened slightly in the 2nd, as was the case with fasting glucose, and HOMA-IR. Other outcomes can be found in the "values" boxes in their respective HEM entries.
Funding issues for this study:
Virta Health Corp.