Studies related to Atrial Fibrillation and Fish oil

Fish Oil Supplementation For Primary Prevention Of Atrial Fibrillation After Coronary Artery Bypass Graft Surgery: A Randomized Clinical Trial

Effect Decrease
Values Incidence: Fish oil: 8.4%; Control: 14.1% (p = 0.07) Episodes of AF: Fish oil: 2; Control: 3.5 (p = 0.06) AF duration: Fish oil: 21.0 hours; Control: 46.9 hours (p= 0.04)
Trial Design Randomized trial
Trial Length 2-4 Weeks
Number of Subjects 401
Sex Both Genders
Age Range 30-44, 45-64
Body Types Overweight, Underweight
Notes for this study:
The main goal of this study was to see if fish oil supplementation affected atrial fibrillation incidence after heart surgery. 401 patients who were about to undergo coronary artery bypass graft surgery were randomized to receive 2 grams fish oil (containing 600 mg EPA and 400 mg DHA) or olive oil placebo daily from four days before surgery until discharge. Post-surgery atrial fibrillation incidence (the primary outcome) did not significantly differ between groups, but there was a possible trend toward a significant reduction in the fish oil group (p = 0.07). However, the fish oil group did tend to have shorter atrial fibrillation episodes, spend less time in the ICU post-surgery, and less time in the hospital overall.
Funding issues for this study:
Fish oil supplier partially funded study