Influence Of Adjuvant Omega-3-polyunsaturated Fatty Acids On Depression, Sleep, And Emotion Regulation Among Outpatients With Major Depressive Disorders - Results From A Double-blind, Randomized And Placebo-controlled Clinical Trial
|Values||ISI. Mean and SD. Placebo: before 17.60 (4.76) , after 10.36 (2.56). Omega-3: before 20.32 (4.22), after 3.48 (1.26).|
|Trial Design||Randomized trial|
|Trial Length||1-6 months|
|Number of Subjects||50|
|Age Range||18-29, 30-44, 45-64, 65+|
In a randomized, double-blind, placebo-controlled trial, 50 participants with major depressive disorders were allocated to take 1000 mg of omega-3 fatty acids or placebo daily for 12 weeks.
There was a statistically significantly greater improvement in both measures of depression, insomnia, and anxiety, in the omega-3 group as compared with the placebo group.