| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 138 |
| Sex | Both Genders |
| Age Range | 45-64 |
| Body Types | Obese |
1.25g or 2.5g of fish oil daily for 4 months in older middle aged obese adults noted that the increase of TNFa in control (12%) was abolished with fish oil and that IL-6 decreased 10-12% with both doses. There was no significant influence on depressive symptoms
