The Effect Of Omega 3 Fatty Acid Supplementation On Premenstrual Syndrome And Health-related Quality Of Life: A Randomized Clinical Trial
Notes for this study:
||SF-12. Mean + SD. Mental symptoms. Placebo: before 39.5 (7.7), after 47.43 (9.5). Fish oil: before 39.1 (9.1), after 48.64 (8.1). Physical symptoms: Placebo: before 48.34 (7.4), after 48.8 (7.7). Omega-3: before 48.58 (7.7), after 50.42 (6.7). PSST symptoms in table 2, generally not notably different
|Number of Subjects
In a randomized, double-blind, placebo-controlled trial, 95 women with premenstrual syndrome were allocated to take 2 g of fish oil yielding 360 mg of EPA and 240 mg of DHA daily or placebo from 8 days before and to 2 days after menstruation for 3 consecutive cycles.
On the modified version of the premenstrual symptoms screening tool (PSST), the only areas where the fish oil group saw notably greater improvement than the placebo group were for insomnia and hypersomnia, the rest being trivially different. Interestingly, in general, both groups saw consistent improvements with each menstrual cycle, compared to the previous. On the SF-12, there was a similar improvement in mental symptoms in both groups and no real difference in physical symptoms.