Efficacy Of Omega-3 For Vasomotor Symptoms Treatment: A Randomized Controlled Trial
Notes for this study:
||Mean and 95% CI. Number of hot flashes. Placebo: before 7.6 (7.0, 8.1), change −2.7 (−3.3, −2.2) Omega-3: before 7.7 (7.1, 8.2),change −2.5 (−3.0, −1.9). Bother (1-4). Placebo: before 2.9 (2.8, 3.0), change −0.5 (−0.6, −0.4). Omega-3: before 3.0 (2.9, 3.1), change −0.5 (−0.6, −0.4)
|Number of Subjects
In a randomized, double-blind, placebo-controlled trial, 355 menopausal or post-menopausal women who were experiencing a high rate of hot flashes were allocated to take 3 capsules containing 425 mg EPA, 100 mg DHA and 15 IU vitamin E daily, or placebo for 12 weeks.
The primary outcome was vasomotor symptoms, and hot flashes were reduced similarly, with no notable or statistically significant difference between groups. There was also no difference in sleep quality, and a greater reduction in depression and anxiety in the placebo group, though the difference wasn't statistically significant. There were no notable differences in adverse events between groups.