Studies related to Leukotriene B4 and Fish Oil

The Effect Of Low-dose Marine N-3 Fatty Acids On The Biosynthesis Of Pro-inflammatory 5-lipoxygenase Pathway Metabolites In Overweight Subjects: A Randomized Controlled Trial

Effect None
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 50
Sex Both Genders
Age Range 30-44, 45-64, 65+
Body Types Obese
Notes for this study:
1.1g of fish oil (640mg EPA and 480mg DHA) daily for 6 weeks was able to reduce levels of Leukotriene B4 within group (but failed when compared to placebo) in serum and no effect was noted on 5-HETE. The eicosanoids known as 5-HEPE (103%) and leukotriene B5 (59%) were both increased.

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