Studies related to Resistin and Vegan Diet

Effect Of Plant-based Diets On Obesity-related Inflammatory Profiles: A Systematic Review And Meta-analysis Of Intervention Trials

Effect None
Trial Design Meta analysis
Trial Length 6+ Months
Number of Subjects 2583
Sex Both Genders
Age Range 18-29, 30-44, 45-64, 65+
Body Types Obese, Overweight
Notes for this study:
This systematic review and meta-analysis of 25 human interventional studies investigated the changes in inflammatory biomarkers as a consequence of adopting a plant-based diet in 2,689 obese and overweight participants.

The median age was 53 years (28–68 years) and the study durations ranged from 6 to 96 weeks. The median BMI of participants was 29 kg m-2.

The following biomarkers of inflammatory status were meta-analyzed: C-reactive protein (CRP), interleukin-6 (IL-6), tumour necrosisfactor-alpha (TNF-ɑ), soluble intercellular adhesion molecule 1 (sICAM), leptin,adiponectin and resistin.

Consumption of a plant-based diet was associated with a reduction in CRP, IL-6, and sICAM. No effects were found for TNF-a, resistin, adiponectin, and leptin.

Overall, a plant-based diet

A major limitation of this meta-analysis is that some studies allowed small amounts of animal products. Hence, the study did not investigate the effects of a vegan diet in a strict sense but merely that of eating a primarily plant-based diet. Another limitation is that the included studies were highly heterogeneous, leading the authors to meta-analyze studies that were too different from each other to be sensibly combined.