Studies related to Lipoprotein A and Vegan Diet

Consumption Of A Defined, Plant-based Diet Reduces Lipoprotein(a), Inflammation, And Other Atherogenic Lipoproteins And Particles Within 4 Weeks

Effect Decrease
Values A vegan diet reduced serum Lp(a) by -32.0 ± 52.3 nmol/L, (P = 0.003) within 4 weeks in 31 obese adults compared to baseline.
Trial Design Non-controlled trial
Trial Length 2-4 Weeks
Number of Subjects 31
Sex Both Genders
Age Range 30-44, 45-64, 65+
Body Types Obese, Overweight
Notes for this study:
This 4-week non-controlled trial examined the effects of a plant-based diet on the lipid levels and inflammation status of 31 obese and overweight midlife and older adults compared to baseline. Lipid levels investigated were: serum lipoprotein A, apolipoprotein B, low-density lipoprotein cholesterol (LDL-C) particles and small dense LDL-C. Inflammation status was assessed by measuring blood levels of high-sensitivity c-reactive protein (hs-CRP).

A vegan diet significantly reduced lipid levels and inflammation status to a modest extent within 4 weeks compared to baseline.

A major limitation in the design of this study was the lack of a control group and the small sample size. Larger sample size and a control group would be needed to strengthen a causal relationship.