The Effects Of Rose Hip (Rosa Canina) On Plasma Antioxidative Activity And C-reactive Protein In Patients With Rheumatoid Arthritis And Normal Controls: A Prospective Cohort Study

Effect None
Trial Design Cohort
Trial Length 1-6 months
Number of Subjects 30
Gender Female
Age Range 45-64
Body Types Average
Notes for this study:
Supplementation of 10.5g rose hip powder daily for four weeks in persons with rheumatoid arthritis as well as a group of healthy controls failed to reduce symptoms of rheumatoid arthritis or to influence biomarkers (red blood cell antioxidant enzymes or C-reactive protein) relative to baseline; no placebo group was used in this study.

Rose Hip Herbal Remedy In Patients With Rheumatoid Arthritis - A Randomised Controlled Trial

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 89
Gender Both Genders
Age Range 45-64, 65+
Body Types Average
Notes for this study:
Rose hip supplementation at 5g for six months in persons with rheumatoid arthritis appeared to show benefits on a health assessment questionnaire (HAQ) at six months yet not three. While there was a trend to improve overall symptoms of rheumatism by clinician rating and DAS-28 rating, the rating scale selectively looking at pain in joints (HAQ patient pain scale) failed to find any benefit. C-reactive protein trended to decrease but failed to reach statistical significance.

Degree of improvement on the global symptoms reached 30% (physician rating) and 19% (DAF-28) relative to baseline values.