Creatine Monohydrate Enhances Strength And Body Composition In Duchenne Muscular Dystrophy
| Effect | None |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 30 |
| Sex | Male |
| Age Range | 7-12 |
| Body Types | Obese, Overweight |
In thirty children given creatine supplementation at around 2-5g daily (half of which were on corticosteroids) for four months of time, supplementation of creatine was associated with an increase in strength of the dominant hand (but not the other) and an almost significant reduction in whole body strength seen in placebo was prevented with creatine.
There were no improvements on activities of daily living or lung function, and there was no influence on DNA damage as assessed by the 8-OH-2-dG/creatinine ratio (but creatinine was also unaffected).
