Studies related to sVCAM-1 and Spirulina

Spirulina Maxima Decreases Endothelial Damage And Oxidative Stress Indicators In Patients With Systemic Arterial Hypertension: Results From Exploratory Controlled Clinical Trial

Effect Decrease
Values (ng/mL) Mean and SD. Placebo: before 508.90 ± 31.40, after 501.60 ± 22.70. Spirulina: before 480.80 ± 10.30 after 458.00 ± 19.60.
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 16
Sex Both Genders
Notes for this study:
In a 12-week randomized, single-blind pilot trial, 16 participants with systemic arterial hypertension who were taking ACE inhibitors took 4.5 g of spirulina maxima or placebo daily.

Blood pressure was reduced more in the spirulina group. There were also improvements in sVCAM-1, sE-Selectin, Endothelin-1 but not sICAM-1. There were also general improvements in antioxidant status, though not oxidative stress.