Spirulina Maxima Improves Insulin Sensitivity, Lipid Profile, And Total Antioxidant Status In Obese Patients With Well-treated Hypertension: A Randomized Double-blind Placebo-controlled Study

Effect Increase
Values TAS (mmol/l) Control: before 1.8 ± 0.2, after 1.8 ± 0.6. Spirulina: before 1.8 ± 0.3, after 2.2 ± 1.0.
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 50
Sex Both Genders
Notes for this study:
In a 3-month randomized, double-blind, placebo-controlled trial, 50 participants with hypertension and obesity took 2 g of spirulina or placebo.

There was a greater reduction in LDL, IL-6, greater increase in total antioxidant state, and insulin sensitivity ratio in the spirulina group. There was less of a reduction in HDL, and the difference between groups at the end was statistically significant. There was a nonsignificantly greater reduction in body mass, total cholesterol, triglycerides, and glucose, and no apparent effect on insulin.

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