| Effect | Decrease |
| Values | (ng/mL). Mean and SD. Placebo: before 13.73 ± 4.16, after 12.40 ± 1.24. Spirulina: before 12.12 ± 1.52 after 9.71 ± 2.13. |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 16 |
| Sex | Both Genders |
In a 12-week randomized, single-blind pilot trial, 16 participants with systemic arterial hypertension who were taking ACE inhibitors took 4.5 g of spirulina maxima or placebo daily.
Blood pressure was reduced more in the spirulina group. There were also improvements in sVCAM-1, sE-Selectin, Endothelin-1 but not sICAM-1. There were also general improvements in antioxidant status, though not oxidative stress.
