Studies related to Working Memory and Bacopa monnieri

Efficacy Of Standardized Extract Of Bacopa Monnieri (Bacognize®) On Cognitive Functions Of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial

Effect Both
Values Mean and SD. Digit span forwards. Placebo: Before 7.83 ± 1.19, after 7.73 ± 0.23. Intervention: before 7.23 ± 1.11, after 7.85 ± 0.83. Digit span backwards. Placebo: Before 9.1 ± 1.0, after 8.3 ± 0.8. Intervention: before 8.1 ± 1.3, after 8.3 ± 0.9. Paired associate task. Placebo: Before 8.1 ± 1.1, after 7.9 ± 1.3. Intervention: before 8 ± 1.3, after 7.7 ± 1.4. Logical memory test Placebo: Before 5.5 ± 2.6, after 4.1 ± 3.8. Intervention: before 3.4 ± 2.6, after 5.2 ± 4.5. Memory Span for nonsense syllables. Placebo: Before 4.7 ± 2.3, after 6.1 ± 2.9. Intervention: before 5.4 ± 3.3, after 6.9 ± 2.4.
Trial Design Randomized trial
Trial Length 24 hours
Number of Subjects 60
Sex Both Genders
Age Range 18-29
Notes for this study:
In a randomized, double-blind placebo-controlled trial, 60 college students aged 19-22 took 50 mg of Bacopa extract, or placebo, twice daily for 1 days. There was a statistically significant improvement in the backward but not forwards, digit span test, and logical memory test. For paired-associate task, finger tapping, memory span for nonsense syllables, simple reaction time, choice reaction time, choice discrimination test, digit picture, and substitution test, there wasn't a statistically significant difference.

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