Studies related to Memory and Bacopa monnieri

Effects Of A Standardized Bacopa Monnieri Extract On Cognitive Performance, Anxiety, And Depression In The Elderly: A Randomized, Double-blind, Placebo-controlled Trial

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 48
Gender Both Genders
Age Range 65+
Notes for this study:
Study conducted in persons over 65 years of age with no signs of dementia with 300mg Bacopa daily for 12 weeks.

Significant improvements in attention (less likely to pay attention to irrelevant information), working memory, and less anxiety and depression.

Also noted a decrease in heart rate, but no changes in blood pressure.

Noted an upset stomach as the only side effect.

Examining The Nootropic Effects Of A Special Extract Of Bacopa Monniera On Human Cognitive Functioning: 90 Day Double-blind Placebo-controlled Randomized Trial

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 62
Gender Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
Used 300mg of Bacopa (KeenMind brand, 55% Bacosides) over 90 days in healthy persons aged 18-60 with no history of mental ailments.

Working memory was increased, as well as precision of rapid identification.

Bacopa group also noted increased energy levels and diarrhea, withdrawals from groups were the same.

Brahmi For The Better? New Findings Challenging Cognition And Anti-anxiety Effects Of Brahmi (Bacopa Monniera) In Healthy Adults

Effect None
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 66
Gender Both Genders
Age Range 30-44, 45-64
Notes for this study:
No influence on any cognitive parameter in otherwise healthy adults following 450mg of Bacopa for 3 months as assessed by the RAVLT test (memory) and Stroop (attention), alongside two other cognitive tests (RVIP and Inspection TIme)

Does Bacopa Monnieri Improve Memory Performance In Older Persons? Results Of A Randomized, Placebo-controlled, Double-blind Trial

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 98
Gender Both Genders
Age Range 65+
Notes for this study:
Study conducted in otherwise healthy persons over the age of 55 with 300mg Bacopa Monnieri (BacoMind) daily for

Improvements noted in verbal learning, memory acquisition and delayed recall as assessed by ALVT.

Statistically insignificant positive trends for reducing rate of forgetting and reducing depressive symptoms.

Side effects of cramps and nausea were more common in the experimental group than placebo group (significantly). Flatulence, bloating, and headaches were not significantly different.

The Acute Effects Of An Extract Of Bacopa Monniera (Brahmi) On Cognitive Function In Healthy Normal Subjects

Effect None
Trial Design Double blind
Trial Length 24 hours
Number of Subjects 38
Gender Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
Study was conducted in 38 healthy adults aged 18-60 and weighing 48-94kg with no memory deficits at a dose of 300mg Bacopa Monnieri. Trial lasted one day as to assess acute effects.

No significant effects of Bacopa Monnieri on any measured parameter were noted.

Chronic Effects Of Brahmi (Bacopa Monnieri) On Human Memory

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 76
Gender Both Genders
Age Range 45-64
Notes for this study:
Study conducted in 76 adults aged 40-65 who had no disease states or signs of dementia, using 300mg for those under 90kg and 450mg for those above 90kg (KeenMind brand)

Retention of new information was increased, but was not due to increased rate of learning. Hypothesized to be due to a lesser rate of forgetting from a hypothalamic anti-oxidant action.

No effects noted on attention.

The Chronic Effects Of An Extract Of Bacopa Monniera (Brahmi) On Cognitive Function In Healthy Human Subjects

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 46
Gender Both Genders
Age Range 18-29, 30-44, 45-64
Body Types Average
Notes for this study:
46 healthy subjects between that ages of 18-60 with 300mg Bacopa Monnieri daily for 12 weeks; testing occurred at 5 and 12 weeks into the study as well as baseline.

Bacopa improved speed of learning, memory capacity, and had greater effects over 12 weeks relative to 5 weeks.

Funded by a Research Grant from KeenMind.

Randomized Controlled Trial Of Standardized Bacopa Monniera Extract In Age-associated Memory Impairment

Effect Increase
Trial Design Double blind
Trial Length n/a
Number of Subjects 86
Gender n/a
Notes for this study:
125mg of Bacopa Monnieri in subjects with age-associated memory impairment over the age of 55; subjects were divided into experimental and placebo for 12 weeks and all subjects underwent placebo for 4 additional weeks.

Improvements seen in various parameters of memory.