Thermotolerance And Heat Acclimation May Share A Common Mechanism In Humans
| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | n/a |
| Number of Subjects | 8 |
| Sex | Both Genders |
| Age Range | 18-29 |
| Body Types | Average |
2g of Quercetin supplementation increased urinary lactulose in healthy adults subject to heat-shock (physical exercise), and after 7 days this increase in urinary lactulose did not decline and the increase in serum endotoxin became statistically significant. The exercise-induced HSP70 induction was abolished with quercetin.
These results suggest that Quercetin at 2g in combination with heat stressors can impair gut permeability.
