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Studies related to Symptoms of Carpal Tunnel and Astaxanthin

A Blinded Placebo-controlled Randomized Trial On The Use Of Astaxanthin As An Adjunct To Splinting In The Treatment Of Carpal Tunnel Syndrome

Effect None
Values CTS Symptom Severity Scale. Mean and SD. Placebo: before 31 (8), after 28 (9). Astaxanthin: before 35 (9), after 31 (10). CTS Functional Scale/40. Placebo: before 18 (8), after 17 (7). Astaxanthin: before 20 (7), after 19 (8).
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 63
Sex Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
In a randomized, triple-blind, placebo-controlled trial, 63 participants with carpal tunnel syndrome were allocated to take 4 mg of astaxanthin daily in addition to splinting, or placebo in addition to splinting for 12 weeks.

The primary outcome was the severity of symptoms as measured by the Symptom Severity Scale for CTS, and there wasn't a statistically significant difference for the change in symptom severity of function between groups. There also wasn't a difference for DASH, SD-36, and impairment measures or electrodiagnostic studies. There was no notable change in lipid profile as well.

No notable difference in side-effects was found, and no moderate or severe adverse events took place.
Funding issues for this study:
"We would like to acknowledge support of Anthony Almada for contributing to study design/oversight of astaxanthin formulation and of IMAGINutrition/Meta Response Sciences for funding of the study."