Efficacy Of Peppermint Oil In Diarrhea Predominant IBS - A Double Blind Randomized Placebo - Controlled Study

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 65
Gender Both Genders
Notes for this study:
Six weeks supplementation of peppermint oil thrice daily was able to reduce symptoms of IBS related to abdominal pain (around 20%) without significantly affecting other symptoms; these benefits were no longer present two weeks after supplement cessation.

Enteric-coated, PH-dependent Peppermint Oil Capsules For The Treatment Of Irritable Bowel Syndrome In Children

Effect Decrease
Trial Design Double blind
Trial Length 1-2 Weeks
Number of Subjects 42
Gender Both Genders
Age Range 7-12, 13-17
Body Types Average
Notes for this study:
0.1mL of peppermint oil thrice daily (or a single dose of 0.2mL) to children with IBS was able to provide relief to pain symptoms associated with the disease state, with 76% of the intervention reporting benefits relative to 19% in placebo.

Treating Irritable Bowel Syndrome With Peppermint Oil

Effect Decrease
Trial Design Double blind
Trial Length 2-4 Weeks
Number of Subjects 16
Gender Both Genders
Notes for this study:
0.2mL of peppermint oil for a period of three weeks in persons with IBS was able to significantly reduce abdominal pain relative to placebo; two patients experienced heartburn.

The Effect Of Enteric-coated, Delayed-release Peppermint Oil On Irritable Bowel Syndrome

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 90
Gender Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
Supplementation of Colpermin peppermint oil capsules in outpatients with IBS was able to significantly reduce the abdominal pain associated with IBS and improve quality of life.

Treatment Of Irritable Bowel Syndrome With Peppermint Oil. A Double-blind Study With A Placebo

Effect Decrease
Trial Design Double blind
Trial Length 2-4 Weeks
Number of Subjects 47
Gender Both Genders
Notes for this study:
200mg of peppermint oil thrice daily (600mg overall) in persons diagnosed with IBS over the course of four weeks was associated with significantly more reductions in global symptoms of IBS relative to placebo.

Peppermint Oil (Mintoil) In The Treatment Of Irritable Bowel Syndrome: A Prospective Double Blind Placebo-controlled Randomized Trial

Effect Decrease
Trial Design Double blind
Trial Length 2-4 Weeks
Number of Subjects 57
Gender Both Genders
Notes for this study:
Four weeks supplementation of 225mg peppermint oil twice daily (450mg overall) was associated with a reduction in symptoms of IBS assessed by how many patients reported over a halving of symptoms, the frequency of which exceeded placebo.

Enteric-coated Peppermint-oil Capsules In The Treatment Of Irritable Bowel Syndrome: A Prospective, Randomized Trial

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 110
Gender Both Genders
Notes for this study:
187mg of peppermint oil thrice to four times daily for a month in persons with IBS was associated with a significant reduction of overall symptoms relative to placebo.

Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis
Effect Decrease
Trial Design meta
Trial Length na
Number of Subjects 392
Gender mixed
Notes for this study:
Global symptoms of IBS were reduced with supplementation of peppermint oil with a reduced risk (relative risk ratio) of 0.43 (95% CI of 0.32-0.59), suggesting about a halving of symptoms.