| Effect | None |
| Values | (ug/L). Mean + SEM. Before 447 (47), after 426 (47) |
| Trial Design | Randomized trial |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 61 |
| Sex | Both Genders |
In a randomized 36 patients with stable angina who had been receiving maintenance hemodialysis and 15 healthy controls were allocated to take 50 ml of a red grape juice concentrate (total polyphenols, 0.64 g/100 mL) twice per day or control (no intervention) for 2 weeks. The healthy participants all received the supplement. In another study, 10 hemodialysis patients were given the red grape juice supplement for 3 weeks.
There were no statistically significant or notable differences between groups for the change in glucose, uric acid, serum protein, or albumin after 2 weeks. There were no significant changes for triglycerides, but total and LDL cholesterol were reduced, HDL was increased, apo-A was increased, and apo B was decreased significantly more in both juice grapes than the control group.
The uncontrolled study of healthy participants consuming the juice found reductions in MCP-1 but not CRP, C3, ICAM-1 or VCAM-1.
