| Effect | Decrease |
| Trial Design | Cohort |
| Trial Length | n/a |
| Number of Subjects | 66 |
| Gender | Both Genders |
In persons with Postoperative and traumatic swelling (knee surgery) given serrapeptase (dose not specified) or a control group of ice and bed rest noted that in the serrapeptase group swelling was reduced by 50% on day 5 and eliminated on day 10. No indication that any placebo controlling was utilized, although randomization was specified
A Multi-centre, Double-blind Study Of Serrapeptase Versus Placebo In Post-antrotomy Buccal Swelling
| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | 1-7 Days |
| Number of Subjects | 174 |
| Gender | Both Genders |
| Age Range | 18-29, 30-44, 45-64 |
In persons given serrapeptase at 30mg (10mg thrice daily) for 7 days after surgery (Caldwell-luc antrotomy) in order to assess buccal swelling noted that the serrapeptase group outperformed placebo in reducing swelling associated with surgery.
