Saffron And Crocin Improved Appetite, Dietary Intakes And Body Composition In Patients With Coronary Artery Disease
Notes for this study:
||mg/dL Mean and SD. Placebo: before 41.74±14.85, after 43.16±13.33. Crocin: before 40.47±18.88, after 42.21±20.89. Saffron: before 45.10±14.92, after 43.65±12.50.
|Number of Subjects
In a randomized, double-blind, placebo-controlled trial, 84 participants with coronary artery disease took an aqueous extract of 30 mg saffron, 30 mg of crocin, or placebo daily for 8 weeks.
There was a greater reduction in body weight, waist circumference, fat mass, and fat percentage, and fat-free mass in the saffron group compared with the others. The crocin group tended to see a greater reduction than the placebo group. The saffron group reported feeling less hungry and more satisfied overall.
There weren't meaningful differences for fasting glucose and lipid profile.
The trial was preregistered: IRCT201512102017N26