Studies related to Lipid Peroxidation and Saffron

Effects Of Saffron Supplementation On Inflammation And Metabolic Responses In Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled Trial

Effect Decrease
Values MDA (μM/L) Mean and SD. Placebo: before 15.8±2.7, after 15.9±2.7. Saffron: before 17.8±0.17, after 16.7±3.5
Trial Design Uncontrolled / observational study
Trial Length n/a
Number of Subjects 90
Sex Both Genders
Notes for this study:
In a randomized, controlled trial, 90 participants with type 2 diabetes took 200 mg of saffron or placebo daily for 12 weeks.

There was a greater reduction in waist circumference in the saffron group, but the differences for body fat %, body weight, and BMI weren't statistically significant. There also weren't statistically significant differences for metabolic, lipid, or inflammatory markers. There was a greater reduction in malondialdehyde but not a significant difference in total antioxidant capacity.

The trial was preregistered: IRCT201510259472N9

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