Studies related to Depression and Saffron

Crocus Sativus L. (saffron) Versus Sertraline On Symptoms Of Depression Among Older People With Major Depressive Disorders-a Double-blind, Randomized Intervention Study

Effect Decrease
Values Hamilton Depression Rating Scale. Saffron: before 21.12 (2.35), after 9.92 (4.51). Sertraline: before 21.40 (2.86), after 8.76 (4.52)
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 50
Sex Both Genders
Age Range 45-64, 65+
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 50 participants over the age of 60 took 60 mg of saffron or 100 mg of sertraline daily for 6 weeks.

Both groups saw a similar reduction in depression.

The trial was preregistered: IRCT20120215009014N204

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