Effect of saffron (Crocus sativus L.) on lipid profile, glycemic indices and antioxidant status among overweight/obese prediabetic individuals: A double-blinded, randomized controlled trial
Notes for this study:
| Effect | Increase |
| Values | DPPH %. Mean and SD. Placebo: before 10.00 ± 3.32, after 9.15 ± 2.94. Saffron: before 11.06 ± 3.24, after 13.46 ± 3.33. |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 75 |
| Sex | Both Genders |
| Age Range | 30-44, 45-64 |
| Body Types | Obese, Overweight |
In a randomized, double-blind, placebo-controlled trial, 75 participants with prediabetes took 15 mg of saffron extract or placebo daily for 8 weeks.
There was a greater reduction in fasting glucose, HbA1c and a greater increase in antioxidant activity via DPPH. There weren't any statistically significant differences between groups for lipid profile, BUN, or creatinine.
The trial was preregistered: IRCT20120913010826N19
