Studies related to Hot Flashes and Saffron

Efficacy Of Crocus Sativus (saffron) In Treatment Of Major Depressive Disorder Associated With Post-menopausal Hot Flashes: A Double-blind, Randomized, Placebo-controlled Trial

Effect Decrease
Values HFRDIS. Reduction and SD after 6 weeks: Placebo: 32.14 ± 20.43 Saffron: 51.78 ± 19.25
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 60
Sex Female
Age Range 30-44, 45-64, 65+
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 60 post-menopausal women with hot flashes took 30 mg of saffron extract or placebo daily for 6 weeks.

Hot flashes and depression were reduced more in the saffron group.

The trial was preregistered: IRCT201602031556N85