| Effect | Decrease |
| Values | HFRDIS. Reduction and SD after 6 weeks: Placebo: 32.14 ± 20.43 Saffron: 51.78 ± 19.25 |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 60 |
| Sex | Female |
| Age Range | 30-44, 45-64, 65+ |
In a randomized, double-blind, placebo-controlled trial, 60 post-menopausal women with hot flashes took 30 mg of saffron extract or placebo daily for 6 weeks.
Hot flashes and depression were reduced more in the saffron group.
The trial was preregistered: IRCT201602031556N85
