| Effect | None |
| Values | Mean and SD. Placebo: before 0.7±0.1, after 0.7±0.1. Crocin, before 0.7±0.1, after 0.8±0.1. Saffron: before 0.7±0.1, after 0.8±0.1 . |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 66 |
| Sex | Both Genders |
| Age Range | 18-29, 30-44, 45-64 |
In a randomized, double-blind, placebo-controlled trial, 66 participants with schizophrenia took 30 mg of saffron aqueous extract or crocin daily, or placebo, for 12 weeks.
The saffron group saw an increase in white blood cell count, but not red blood cells, hemoglobin, hematocrit, or platelets. There weren't statistically significant differences for liver enzymes, urea, creatinine, erythrocyte sedimentation rate, c-reactive protein, T3, T4, or TSH, though TSH increased in the saffron group.
The trial was preregistered: IRCT2013020312351N1
