Melatonin Responses To Clonidine And Yohimbine Challenges
Effect | Increase |
Trial Design | Double blind |
Trial Length | 24 hours |
Number of Subjects | 10 |
Sex | Female |
Age Range | 18-29, 30-44 |
Body Types | Average |
Supplementation of 10.8mg yohimbine in the evening (6pm, measuring until 10pm) failed to modify plasma melatonin concentrations despite increased urinary excretion; the volunteers had an increased urge to urinate in the morning after.