Studies related to Cortisol and Yohimbine

Psychological And Neuroendocrine Responses To Social Stress And To The Administration Of The Alpha-2-receptor Antagonist, Yohimbine, In Highly Trained Endurance Athletes In Comparison To Untrained Healthy Controls

Effect Increase
Trial Design Double blind
Trial Length n/a
Number of Subjects 24
Sex n/a
Notes for this study:
Yohimbine, at 0.4mg/kg bodyweight, was able to increase anxiety and cortisol as well as the heart parameters of blood pressure and heart rate, in both inactive and active healthy males.

Cortisol increased in the untrained persons, and not the trained athletes (who had higher baseline cortisol levels), but anxiety increased in both groups 20-40 minutes after ingestion.

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