Psychological And Neuroendocrine Responses To Social Stress And To The Administration Of The Alpha-2-receptor Antagonist, Yohimbine, In Highly Trained Endurance Athletes In Comparison To Untrained Healthy Controls
|Trial Design||Double blind|
|Number of Subjects||24|
Yohimbine, at 0.4mg/kg bodyweight, was able to increase anxiety and cortisol as well as the heart parameters of blood pressure and heart rate, in both inactive and active healthy males.
Cortisol increased in the untrained persons, and not the trained athletes (who had higher baseline cortisol levels), but anxiety increased in both groups 20-40 minutes after ingestion.