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| Effect | Decrease |
| Values | Fasting glucose (mg/dl): Placebo: before 160.75 ± 2.60 mg/dl, after 155.33 ± 2.31. Vitamin C: before 157.63 ± 3.13, after 141.18 ± 3.81. Postprandial blood glucose: Placebo: before 218.51 ± 3.53, after 211.57 ± 2.88. Vitamin C: before 222.24 ± 3.16, after 206.69 ± 3.31 |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 70 |
| Sex | Both Genders |
| Age Range | 30-44, 45-64 |
In a randomized, double-blind, placebo-controlled study, 70 participants with type 2 diabetes who were taking metformin received 500 mg of vitamin C twice daily (1000 mg per day) or a placebo. After 12 weeks, the participants who received vitamin C saw a modest and significant reduction in fasting blood glucose, postprandial blood glucose, and Hba1c compared with the placebo group. All of the participants in the study were advised to minimize foods rich in vitamin C in their diets throughout the study. This, however, didn't reduce plasma vitamin C concentrations in the placebo group, while the vitamin C group saw a significant increase.
