EFFECT OF ORAL SUPPLEMENTATION OF VITAMIN C ON GLYCEMIC CONTROL AND LIPID PROFILE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Notes for this study:
|Values||Within-group (mg/dl) Before 33±5.92, after 29.71±7.27|
|Trial Design||Randomized trial|
|Trial Length||1-6 months|
|Number of Subjects||65|
|Age Range||30-44, 45-64, 65+|
|Body Types||Obese, Overweight, Average|
In a randomized, controlled, open label trial, 65 participants with type 2 diabetes were enrolled and 59 made it to follow-up. Participants in the vitamin C group took 500 mg of vitamin C once a day for 3 months.
Compared with baseline, after 3 months, the vitamin C group saw small reductions in fasting glucose, HbA1c, and blood pressure which were not statistically significant, while these measures worsened in the control group. The worsening in the control group was statistically significant for systolic and diastolic blood pressure while the increase in fasting glucose and HbA1c wasn't. The vitamin C group saw modest, statistically significant reductions in total and LDL cholesterol, whereas the changes in triglycerides and HDL cholesterol were not statistically significant. The control group saw a slight worsening effect in these measures which wasn't statistically significant.