| Effect | Increase |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 75 |
| Sex | Male |
After 5 g of withania somnifera root powder daily, sperm quality increased in all three tested groups (three types of male infertility, fertile men were not tested); sperm concentration, overall volume, motility, and count all increased. All tested groups experienced an increase in anti-oxidant enzymes in the semen and a decrease in oxidative products, with the Normozoospermic group having greater levels of catalase than control.
Testosterone and Luteinizing hormone were increased (trend to normalization to control group) and follicle stimulating hormone decreased (trend to normalization with control) in tested groups; fertile men were not tested.
