Studies related to Thyroid-Stimulating Hormone and Ashwagandha

Efficacy And Safety Of Ashwagandha Root Extract In Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial

Effect Decrease
Values (uIU/mL). Placebo: before 6.72 (0.93, after 7.05 (1.93). Ashwagandha: before 6.48 (0.85), after 5.35 (1.08)
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 50
Sex Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 50 participants with subclinical hypothyroidism were assigned to take 600 mg of a 100% aqueous extract of ashwagandha (5% withanolides) or placebo daily for 8 weeks.

There was a notable, statistically significant increase in T3 and T4 and a notable reduction in TGH in the ashwagandha group compared with the placebo group.

There was no notable difference between groups for adverse events.