| Effect | Decrease |
| Values | (uIU/mL). Placebo: before 6.72 (0.93, after 7.05 (1.93). Ashwagandha: before 6.48 (0.85), after 5.35 (1.08) |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 50 |
| Sex | Both Genders |
| Age Range | 18-29, 30-44, 45-64 |
In a randomized, double-blind, placebo-controlled trial, 50 participants with subclinical hypothyroidism were assigned to take 600 mg of a 100% aqueous extract of ashwagandha (5% withanolides) or placebo daily for 8 weeks.
There was a notable, statistically significant increase in T3 and T4 and a notable reduction in TGH in the ashwagandha group compared with the placebo group.
There was no notable difference between groups for adverse events.
