Efficacy And Safety Of Ashwagandha (Withania Somnifera) Root Extract In Insomnia And Anxiety: A Double-blind, Randomized, Placebo-controlled Study
Notes for this study:
||(min). Mean and SD. Placebo: before 41.95 (6.99), after 33.95 (7.66). Ashwagandha: before 41.62 (6.84), after 29.00 (7.15).
|Number of Subjects
||18-29, 30-44, 45-64
In a randomized, double-blind, placebo-controlled trial, 60 participants who had been diagnosed with insomnia were allocated to take placebo or 300 mg of an ashwagandha extract derived from roots with 5% withanolides for 10 weeks.
Funding issues for this study:
The primary outcome was sleep onset latency, as assessed by actigraphy. At the end of 10 weeks, sleep onset latency had considerably improved in both groups, with a somewhat greater improvement in the ashwagandha group that was statistically significant compared with the placebo. The same was the case for sleep efficiency, and the greater improvement in the ashwagandha group was almost statistically significant for total sleep time and time awake after sleep onset (p=0.076). Sleep quality on The Pittsburgh Sleep Quality Index (PSQI) was improved more in the ashwagandha group, and the difference was statistically significant, and as was the score on the Hamilton Anxiety Rating Scale (HAM-A).
Unclear funding but the authors declare that there were no competing interests.