Efficacy And Safety Of Ashwagandha (Withania Somnifera (L.) Dunal) Root Extract In Improving Memory And Cognitive Functions
Notes for this study:
||Wechsler Memory Scale (WMS-III INDIA) working memory subset: Letter numbering sequence . Placebo: before 12.85 (2.15), after 13.08. Ashwagandha: before 11.88 (2.86), after 12.88 (1.74). Insignificant. Spatial span: Placebo: before 11.65 (3.54), after 11.69 (1.59). Ashwagandha: before 12.12 (3.31), after 1.71 (1.69). Significant.
|Number of Subjects
||30-44, 45-64, 65+
||Obese, Overweight, Average
In a randomized, double-blind, placebo-controlled trial, 50 subjects with memory impairment, early dementia, or a low score on a general cognitive function test took either placebo or 600 mg of an ashwagandha root extract for 8 weeks.
The primary outcome was considered to be performance on various cognitive tests, including memory, visuospatial processing, executive function, and attention. At the end of 8 weeks, participants taking ashwagandha saw statistically significant improvements compared with the placebo group in most memory tests, executive function, and attention, though not visuospatial processing.